Guillain-Barre syndrome in children.

Comparison of Immunoblotting and ELISA for Detection of Anti-Ganglioside Antibodies in Children with Guillain-Barre Syndrome

Background: Anti-ganglioside antibody assays are widely used for diagnosis of autoimmune peripheral neuropathies. Objective: This study aimed to determine serum levels of anti-ganglioside antibodies in children with Guillain-Barre syndrome by immunoblotting technique and compare the results with those obtained by ELISA method. Method: In this investigation, 50 children with Guillain-Barre syndr...

Predictive Factors of Respiratory Failure in Children with Guillain-Barre Syndrome

Introduction:Guillain-Barre Syndrome(GBS) is the most common cause of acute flaccid paralysis. Respiratory failure is the most serious short-term complication of GBS and invasive mechanical ventilation is required in 30% of patients.moreover,60% of those who are intubated develop major complications including pnemonia,sepsis,GI bleeding and pulmonary embolism. Thus respiratory failure predictio...

EPIDEMIOLOGICAL, CLINICAL AND ELECTRODIAGNOSTIC FINDINGS IN CHILDHOOD GUILLAIN-BARRE SYNDROME

In order to identify the clinical and electrophysiological characteristics of childhood Guillain-Barre Syndrome (GBS) in East Azarbaijan province, clinical and electrophysiological data on 40 consecutive children with GBS, admitted to Tabriz Children's Medical Center from March 21st 1999 to March 20th 2002, were analyzed. All patients received intravenous immunoglobulin, 400 mg /kg/ day fo...

Detection of Anti-Ganglioside Antibodies in Guillain-Barre Syndrome

Ten-year Investigation of Clinical and Laboratory Findings in children with Guillain-Barre Syndrome in Sari Bou-Ali Sina Hospital

Background and purpose: Guillain-Barre syndrome (GBS) is an autoimmune disorder that has different clinical and pathologic findings. Its diagnosis is based on clinical findings. This study aimed at investigating the characteristics of the disease in a region in north of Iran. Materials and methods: In this descriptive-analytical study, the records (2008-2018) of children under the age of 15 ye...

Guillain-Barre’ Syndrome: A Case Report

Background and Objectives: Guillain-Barre´ Syndrome (GBS) is an acute-onset, monophasic, immune-mediated polyneuropathy that often follows an antecedent infection. Special nutritional support has an important role in these patients. Methods: A 6 years old girl with GBS was admitted to PICU of Dr. Sheikh Children Hospital (Mashhad, Iran). Chief compliance for hospitalization was inability to w...